Recently, Professor Zhiqiang Yan's team from Capital Medical University and Chinese Institutes for Medical Research (CIMR), Beijing published a comprehensive review  titled "TMC1 and TMC2 function as the mechano-electrical transduction ion channel in hearing" in the journal Current Opinion in Neurobiology. This review systematically consolidates the critical evidence that establishes TMC1 and TMC2 as the primary mechanotransduction ion channels responsible for auditory perception. The article not only elucidates the intricate gating mechanisms of these channels but also provides a forward-looking perspective on future research avenues, highlighting potential areas for further investigation and innovation.

 

 

Fulltext link: https://www.sciencedirect.com/science/article/pii/S0959438825000571

 

Professor and Dean, School of Basic Medical Sciences, Capital Medical University, China. Investigator and Director, Institute for Medical Physiology, Chinese Institutes for Medical Research, Beijing, China.

The Yan laboratory studies sensory neurobiology, focuses on identifying the receptors and neural circuits for sensation and interoception, studies their working mechanism and related the diseases in sensory system.

 

Learn more at: https://www.cimrbj.ac.cn/en/channel/1849736840060473344.html